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Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.
grade
ACS reagent
Quality Segment
agency
reag. Ph. Eur.
vapor pressure
<0.1 hPa ( 20 °C)
form
solid
potency
8471 mg/kg LD50, oral (Rat), 8200 mg/kg LD50, skin (Rat)
technique(s)
titration: suitable
pH
9 (20 °C, 100 g/L in H2O)
mp
132-135 °C (lit.)
density
1.335 g/mL at 25 °C (lit.)
bulk density
720‑760 kg/m3
storage temp.
15-25°C
SMILES string
NC(N)=O
InChI
1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
InChI key
XSQUKJJJFZCRTK-UHFFFAOYSA-N
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